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Comparison of efficiency and specificity of CRISPR-associated (Cas) nucleases...
Molecular tools adapted from bacterial CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats) systems for adaptive immunity have become widely used for plant genome... -
SPECTRE: a Suite of PhylogEnetiC Tools for Reticulate Evolution
Split-networks are a generalization of phylogenetic trees that have proven to be a powerful tool in phylogenetics. Various ways have been developed for computing such networks,... -
Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations ov...
Crop disease outbreaks are often associated with clonal expansions of single pathogenic lineages. To determine whether similar boom-and-bust scenarios hold for wild... -
Albugo candida race diversity, ploidy and host-associated microbes revealed ...
Physiological races of the oomycete Albugo candida are biotrophic pathogens of diverse plant species, primarily the Brassicaceae, and cause infections that suppress host... -
Genome Variation and Molecular Epidemiology of Salmonella enterica Serovar Ty...
Salmonella enterica serovar Typhimurium is one of approximately 2,500 distinct serovars of the genus Salmonella but is exceptional in its wide distribution in the environment,... -
Omics Approaches to Identify Potential Biomarkers of Inflammatory Diseases in...
Inflammatory diseases such as inflammatory bowel disease (IBD) require recurrent invasive tests, including blood tests, radiology, and endoscopic evaluation both to diagnose and... -
A Single Community Dominates Structure and Function of a Mixture of Multiple ...
The ecology of microbes frequently involves the mixing of entire communities (community coalescence), for example, flooding events, host excretion, and soil tillage, yet the... -
CropSight: a scalable and open-source information management system for distr...
High-quality plant phenotyping and climate data lay the foundation for phenotypic analysis and genotype-environment interaction, providing important evidence not only for plant... -
Convergent gene loss in aquatic plants predicts new components of plant immun...
The transition of plants from sea to land sparked an arms race with pathogens. The increased susceptibility of land plants is largely thought to be due to their dependence on... -
Integrating a newly developed BAC-based physical mapping resource for Lolium ...
Lolium perenne (perennial ryegrass) is the most widely cultivated forage and amenity grass species in temperate areas worldwide and there is a need to understand the genetic... -
Comparative analysis of targeted long read sequencing approaches for characte...
The Oxford Nanopore Technologies MinION™ sequencer is a small, portable, low cost device that is accessible to labs of all sizes and attractive for in-the-field sequencing... -
Repeat associated mechanisms of genome evolution and function revealed by the...
Understanding the mechanisms driving lineage-specific evolution in both primates and rodents has been hindered by the lack of sister clades with a similar phylogenetic structure... -
Integration of transcriptomic and metabolic data reveals hub transcription fa...
Drought is one of the most important environmental stresses that effects crop productivity in many agricultural regions. Sunflower is tolerant to drought conditions but the... -
Transcriptomic and metabolic responses of Calotropis procera to salt and drou...
Calotropis procera is a wild plant species in the family Apocynaceae that is able to grow in harsh, arid and heat stressed conditions. Understanding how this highly adapted... -
Aequatus: an open-source homology browser
Phylogenetic information inferred from the study of homologous genes helps us to understand the evolution of genes and gene families, including the identification of ancestral... -
LC3-Associated Phagocytosis Is Required for Dendritic Cell Inflammatory Cytok...
The human fungal microbiota known as mycobiota is increasingly recognized as a critical factor in human gut health and disease. Nonpathogenic commensal yeasts such as... -
A gene expression signature in developing Purkinje cells predicts autism and ...
Autism spectrum disorder (ASD) is a complex neurodevelopmental disease whose underpinning molecular mechanisms and neural substrates are subject to intense scrutiny.... -
ReGaTE: Registration of Galaxy Tools in Elixir
Bioinformaticians routinely use multiple software tools and data sources in their day-to-day work and have been guided in their choices by a number of cataloguing initiatives.... -
Exploiting the ZIP4 homologue within the wheat Ph1 locus has identified two l...
Despite possessing related ancestral genomes, hexaploid wheat behaves as a diploid during meiosis. The wheat Ph1 locus promotes accurate synapsis and crossover of homologous... -
CRISPR-based tools for plant genome engineering
Molecular tools adapted from bacterial CRISPR (clustered regulatory interspaced short palindromic repeat) adaptive immune systems have been demonstrated in an increasingly wide...