Exploiting the ZIP4 homologue within the wheat Ph1 locus has identified two lines exhibiting homoeologous crossover in wheat-wild relative hybrids

Despite possessing related ancestral genomes, hexaploid wheat behaves as a diploid during meiosis. The wheat Ph1 locus promotes accurate synapsis and crossover of homologous chromosomes. Interspecific hybrids between wheat and wild relatives are exploited by breeders to introgress important traits from wild relatives into wheat, although in hybrids between hexaploid wheat and wild relatives, which possess only homoeologues, crossovers do not take place during meiosis at metaphase I. However, in hybrids between Ph1 deletion mutants and wild relatives, crossovers do take place. A single Ph1 deletion (ph1b) mutant has been exploited for the last 40 years for this activity. We show here that chemically induced mutant lines, selected for a mutation in TaZIP4-B2 within the Ph1 locus, exhibit high levels of homoeologous crossovers when crossed with wild relatives. Tazip4-B2 mutant lines may be more stable over multiple generations, as multivalents causing accumulation of chromosome translocations are less frequent. Exploitation of such Tazip4-B2 mutants, rather than mutants with whole Ph1 locus deletions, may therefore improve introgression of wild relative chromosome segments into wheat.

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Author Rey, María-Dolores
Last Updated November 20, 2019, 16:49 (UTC)
Created August 1, 2019, 10:30 (UTC)
Article Host Type publisher
Article Is Open Access true
Article License Type cc-by
Article Version Type publishedVersion
Citation Report https://scite.ai/reports/10.1007/s11032-017-0700-2
DOI 10.1007/s11032-017-0700-2
Date Last Updated 2019-01-02T22:31:51.130716
Evidence open (via page says license)
Funder code(s) Biotechnology and Biological Sciences Research Council (Grant BB/M009599/1, Grant BB/J007188/1, Grant BB/J004588/1); Marie Curie Fellowship Grant (H2020-MSCA-IF-2015-703117)
Journal Is Open Access false
Open Access Status hybrid
PDF URL https://link.springer.com/content/pdf/10.1007%2Fs11032-017-0700-2.pdf
Publisher URL https://doi.org/10.1007/s11032-017-0700-2