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Harnessing plant metabolic diversity
Advances in DNA sequencing and synthesis technologies in the twenty-first century are now making it possible to build large-scale pipelines for engineering plant natural product... -
MinION Analysis and Reference Consortium: Phase 2 data release and analysis o...
Long-read sequencing is rapidly evolving and reshaping the suite of opportunities for genomic analysis. For the MinION in particular, as both the platform and chemistry develop,... -
Opening options for material transfer
The Open Material Transfer Agreement is a material-transfer agreement that enables broader sharing and use of biological materials by biotechnology practitioners working within... -
Adaptation and conservation insights from the koala genome
The koala, the only extant species of the marsupial family Phascolarctidae, is classified as ‘vulnerable’ due to habitat loss and widespread disease. We sequenced the koala... -
Experimental evidence for rapid genomic adaptation to a new niche in an adapt...
A substantial part of biodiversity is thought to have arisen from adaptive radiations in which one lineage rapidly diversified into multiple lineages specialized to many... -
Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations ov...
Crop disease outbreaks are often associated with clonal expansions of single pathogenic lineages. To determine whether similar boom-and-bust scenarios hold for wild... -
Albugo candida race diversity, ploidy and host-associated microbes revealed ...
Physiological races of the oomycete Albugo candida are biotrophic pathogens of diverse plant species, primarily the Brassicaceae, and cause infections that suppress host... -
Omics Approaches to Identify Potential Biomarkers of Inflammatory Diseases in...
Inflammatory diseases such as inflammatory bowel disease (IBD) require recurrent invasive tests, including blood tests, radiology, and endoscopic evaluation both to diagnose and... -
A Single Community Dominates Structure and Function of a Mixture of Multiple ...
The ecology of microbes frequently involves the mixing of entire communities (community coalescence), for example, flooding events, host excretion, and soil tillage, yet the... -
Integration of transcriptomic and metabolic data reveals hub transcription fa...
Drought is one of the most important environmental stresses that effects crop productivity in many agricultural regions. Sunflower is tolerant to drought conditions but the... -
A gene expression signature in developing Purkinje cells predicts autism and ...
Autism spectrum disorder (ASD) is a complex neurodevelopmental disease whose underpinning molecular mechanisms and neural substrates are subject to intense scrutiny.... -
Exploiting the ZIP4 homologue within the wheat Ph1 locus has identified two l...
Despite possessing related ancestral genomes, hexaploid wheat behaves as a diploid during meiosis. The wheat Ph1 locus promotes accurate synapsis and crossover of homologous... -
NLR diversity, helpers and integrated domains: making sense of the NLR IDentity
Plant innate immunity relies on genetically predetermined repertoires of immune receptors to detect pathogens and trigger an effective immune response. A large proportion of... -
Introducing the Brassica Information Portal: Towards integrating genotypic an...
The Brassica Information Portal (BIP) is a centralised repository for Brassica phenotypic data. Trait data associated with Brassica research and breeding experiments conducted... -
A chromosome conformation capture ordered sequence of the barley genome
The International Barley Genome Sequencing Consortium reports sequencing and assembly of a reference genome for barley, Hordeum vulgare. -
Coordination of robust single cell rhythms in the Arabidopsis circadian clock...
The Arabidopsis circadian clock orchestrates gene regulation across the day/night cycle. Although a multiple feedback loop circuit has been shown to generate the 24-hr rhythm,... -
Gaining insight into plant gene transcription using smFISH
ABSTRACT Single molecule RNA fluorescent in situ hybridization (smFISH) enables gene transcription to be assessed at the cellular level. In this point of view article, we... -
Y Chromosome Sequences Reveal a Short Beringian Standstill, Rapid Expansion, ...
The Americas were the last inhabitable continents to be occupied by humans, with a growing multidisciplinary consensus for entry 15–25 thousand years ago (kya) from northeast... -
An automated quantitative image analysis tool for the identification of micro...
High throughput confocal imaging poses challenges in the computational image analysis of complex subcellular structures such as the microtubule cytoskeleton. Here, we developed... -
Plant metabolic engineering in the synthetic biology era: plant chassis selec...
In the July 2017 Gordon Research Conference on Plant Metabolic Engineering that was held in Waterville Valley, New Hampshire, an intriguing discussion began. This discussion...