NLR diversity, helpers and integrated domains: making sense of the NLR IDentity

Plant innate immunity relies on genetically predetermined repertoires of immune receptors to detect pathogens and trigger an effective immune response. A large proportion of these receptors are from the Nucletoide Binding Leucine Rich Repeat (NLR) gene family. As plants live longer than most pathogens, maintaining diversity of NLRs and deploying efficient ‘pathogen traps’ is necessary to withstand the evolutionary battle. In this review, we summarize the sources of diversity in NLR plant immune receptors giving an overview of genomic, regulatory as well as functional studies, including the latest concepts of NLR helpers and NLRs with integrated domains.

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Current Opinion in Plant Biology
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Current Opinion in Plant Biology
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Current Opinion in Plant Biology
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Field	Value
Source
Version
Authors
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Article Host Type	publisher
Article Is Open Access	true
Article License Type	cc-by-nc-nd
Article Version Type	publishedVersion
Citation Report	https://scite.ai/reports/10.1016/j.pbi.2017.04.012
DOI	10.1016/j.pbi.2017.04.012
Date Last Updated	2019-08-01T10:30:14.646467
Evidence	open (via crossref license)
Funder code(s)	BBSRC Institute Strategic Programme Grant (BB/J004669/1); BBSRC Norwich Research Park Bioscience Doctoral Training Grant (BB/M011216/1)
Journal Is Open Access	false
Open Access Status	hybrid
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Publisher URL	https://doi.org/10.1016/j.pbi.2017.04.012