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microRNAs associated with early neural crest development in Xenopus laevis
The neural crest (NC) is a class of transitory stem cell-like cells unique to vertebrate embryos. NC cells arise within the dorsal neural tube where they undergo an epithelial... -
An automated quantitative image analysis tool for the identification of micro...
High throughput confocal imaging poses challenges in the computational image analysis of complex subcellular structures such as the microtubule cytoskeleton. Here, we developed... -
Comparison of Efficiency and Specificity of CRISPR-Associated (Cas) Nucleases...
Molecular tools adapted from bacterial CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats) systems for adaptive immunity have become widely used for plant genome... -
Leaf-GP: an open and automated software application for measuring growth phen...
Background Plants demonstrate dynamic growth phenotypes that are determined by genetic and environmental factors. Phenotypic analysis of growth features over time is a key... -
Independent assessment and improvement of wheat genome assemblies using Fosil...
The accurate sequencing and assembly of very large, often polyploid, genomes remain a challenging task, limiting long range sequence information and phased sequence variation... -
Shifting the limits in wheat research and breeding using a fully annotated re...
An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding... -
The Structure of a Conserved Telomeric Region Associated with Variant Antigen...
African trypanosomiasis is a vector-borne disease of humans and livestock caused by African trypanosomes (Trypanosoma spp.). Survival in the vertebrate bloodstream depends on... -
An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream...
There are hundreds of Trypanosoma species that live in the blood and tissue spaces of their vertebrate hosts. The vast majority of these do not have the ornate system of... -
Plant metabolic engineering in the synthetic biology era: plant chassis selec...
In the July 2017 Gordon Research Conference on Plant Metabolic Engineering that was held in Waterville Valley, New Hampshire, an intriguing discussion began. This discussion... -
New approaches for metagenome assembly with short reads
In recent years, the use of longer range read data combined with advances in assembly algorithms has stimulated big improvements in the contiguity and quality of genome... -
Transcriptomic analysis of salt stress responsive genes in Rhazya stricta
Rhazya stricta is an evergreen shrub that is widely distributed across Western and South Asia, and like many other members of the Apocynaceae produces monoterpene indole... -
Data management and best practice for plant science
Plant research produces data in a profusion of types and scales, and in ever-increasing volume. What are the challenges and opportunities presented by data management in... -
The first near-complete assembly of the hexaploid bread wheat genome, Triticu...
Common bread wheat, Triticum aestivum, has one of the most complex genomes known to science, with 6 copies of each chromosome, enormous numbers of near-identical sequences... -
Genome-Wide Transcription During Early Wheat Meiosis Is Independent of Synaps...
Polyploidization is a fundamental process in plant evolution. One of the biggest challenges faced by a new polyploid is meiosis, particularly discriminating between multiple... -
ViCTree: an automated framework for taxonomic classification from protein seq...
The increasing rate of submission of genetic sequences into public databases is providing a growing resource for classifying the organisms that these sequences represent. To aid... -
Heterarchy of transcription factors driving basal and luminal cell phenotypes...
Heterarchy of transcription factors driving basal and luminal cell phenotypes in human urothelium -
Convergent evolution of SWS2 opsin facilitates adaptive radiation of threespi...
Repeated adaptation to a new environment often leads to convergent phenotypic changes whose underlying genetic mechanisms are rarely known. Here, we study adaptation of color... -
Efficient and accurate detection of splice junctions from RNA-seq with Portcu...
Next-generation sequencing technologies enable rapid and cheap genome-wide transcriptome analysis, providing vital information about gene structure, transcript expression, and... -
Integrative analysis of Paneth cell proteomic and transcriptomic data from in...
Paneth cells are key epithelial cells that provide an antimicrobial barrier and maintain integrity of the small-intestinal stem cell niche. Paneth cell abnormalities are... -
Speed breeding is a powerful tool to accelerate crop research and breeding
The growing human population and a changing environment have raised significant concern for global food security, with the current improvement rate of several important crops...
