Shifting the limits in wheat research and breeding using a fully annotated reference genome

An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage–related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.

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Author null, null
Last Updated November 20, 2019, 16:48 (UTC)
Created August 1, 2019, 10:28 (UTC)
Article Host Type repository
Article Is Open Access true
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Article Version Type publishedVersion
Citation Report https://scite.ai/reports/10.1126/science.aar7191
DOI 10.1126/science.aar7191
Date Last Updated 2019-07-25T09:27:37.690859
Evidence oa repository (via OAI-PMH title match)
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Journal Is Open Access false
Open Access Status green
PDF URL http://pure-oai.bham.ac.uk/ws/files/54477981/IWGSC_RefSeqv1.0.pdf
Publisher URL http://research-repository.uwa.edu.au/en/publications/shifting-the-limits-in-wheat-research-and-breeding-using-a-fully-annotated-reference-genome(8883a580-b33c-4558-b37f-291af8c61c84).html