Transcriptional and environmental control of bacterial denitrification and N2O emissions

In oxygen-limited environments, denitrifying bacteria can switch from oxygen-dependent respiration to nitrate (NO3−) respiration in which the NO3− is sequentially reduced via nitrite (NO2−), nitric oxide (NO) and nitrous oxide (N2O) to dinitrogen (N2). However, atmospheric N2O continues to rise, a significant proportion of which is microbial in origin. This implies that the enzyme responsible for N2O reduction, nitrous oxide reductase (NosZ), does not always carry out the final step of denitrification either efficiently or in synchrony with the rest of the pathway. Despite a solid understanding of the biochemistry underpinning denitrification, there is a relatively poor understanding of how environmental signals and respective transcriptional regulators control expression of the denitrification apparatus. This minireview describes the current picture for transcriptional regulation of denitrification in the model bacterium, Paracoccus denitrificans, highlighting differences in other denitrifying bacteria where appropriate, as well as gaps in our understanding. Alongside this, the emerging role of small regulatory RNAs in regulation of denitrification is discussed. We conclude by speculating how this information, aside from providing a better understanding of the denitrification process, can be translated into development of novel greenhouse gas mitigation strategies.

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Author Gaimster, Hannah
Last Updated November 20, 2019, 16:54 (UTC)
Created November 19, 2019, 14:39 (UTC)
Article Host Type repository
Article Is Open Access true
Article License Type
Article Version Type acceptedVersion
Citation Report https://scite.ai/reports/10.1093/femsle/fnx277
DOI 10.1093/femsle/fnx277
Date Last Updated 2019-11-15T12:57:17.789295
Evidence oa repository (via OAI-PMH doi match)
Funder code(s) Biotechnology and Biological Sciences Research Council (BB/L022796/1)
Journal Is Open Access false
Open Access Status green
PDF URL https://ueaeprints.uea.ac.uk/65807/1/Gaimster_et_al._2017.pdf
Publisher URL https://academic.oup.com/femsle/article/365/5/fnx277/4768087