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Rapid profiling of the preterm infant gut microbiota using nanopore sequencin...
The Oxford Nanopore MinION sequencing platform offers near real time analysis of DNA reads as they are generated, which makes the device attractive for in-field or clinical... -
Aequatus: An open-source homology browser
Phylogenetic information inferred from the study of homologous genes helps us to understand the evolution of genes and gene families, including the identification of ancestral... -
A four-group urine risk classifier for predicting outcomes in patients with p...
Objectives To develop a risk classifier using urine‐derived extracellular vesicle (EV)‐RNA capable of providing diagnostic information on disease status prior to biopsy, and... -
NODULE INCEPTION Recruits the Lateral Root Developmental Program for Symbioti...
To overcome nitrogen deficiencies in the soil, legumes enter symbioses with rhizobial bacteria that convert atmospheric nitrogen into ammonium. Rhizobia are accommodated as... -
CausalTAB: the PSI-MITAB 2.8 updated format for signalling data representatio...
Abstract Motivation Combining multiple layers of information underlying biological complexity into a structured framework represent a challenge in systems biology. A key... -
A Galaxy-based training resource for single-cell RNA-seq quality control and ...
Background It is not a trivial step to move from single-cell RNA-seq (scRNA-seq) data production to data analysis. There is a lack of intuitive training materials and... -
A world of opportunities with nanopore sequencing
Oxford Nanopore Technologies' MinION sequencer was launched in pre-release form in 2014 and represents an exciting new sequencing paradigm. The device offers multi-kilobase... -
Hidden variation in polyploid wheat drives local adaptation
Wheat has been domesticated into a large number of agricultural environments and has a remarkable ability to adapt to diverse environments. To understand this process, we survey... -
Harnessing plant metabolic diversity
Advances in DNA sequencing and synthesis technologies in the twenty-first century are now making it possible to build large-scale pipelines for engineering plant natural product... -
Opening options for material transfer
The Open Material Transfer Agreement is a material-transfer agreement that enables broader sharing and use of biological materials by biotechnology practitioners working within... -
Adaptation and conservation insights from the koala genome
The koala, the only extant species of the marsupial family Phascolarctidae, is classified as ‘vulnerable’ due to habitat loss and widespread disease. We sequenced the koala... -
Increased transcriptional and metabolic capacity for lipid metabolism in the ...
The human prostate gland comprises three distinct anatomical glandular zones, namely the peripheral, central and transitional zones. Although prostate cancer can arise... -
An improved assembly and annotation of the allohexaploid wheat genome identif...
Advances in genome sequencing and assembly technologies are generating many high-quality genome sequences, but assemblies of large, repeat-rich polyploid genomes, such as that... -
Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations ov...
Crop disease outbreaks are often associated with clonal expansions of single pathogenic lineages. To determine whether similar boom-and-bust scenarios hold for wild... -
Albugo candida race diversity, ploidy and host-associated microbes revealed ...
Physiological races of the oomycete Albugo candida are biotrophic pathogens of diverse plant species, primarily the Brassicaceae, and cause infections that suppress host... -
Genome Variation and Molecular Epidemiology of Salmonella enterica Serovar Ty...
Salmonella enterica serovar Typhimurium is one of approximately 2,500 distinct serovars of the genus Salmonella but is exceptional in its wide distribution in the environment,... -
Convergent gene loss in aquatic plants predicts new components of plant immun...
The transition of plants from sea to land sparked an arms race with pathogens. The increased susceptibility of land plants is largely thought to be due to their dependence on... -
Integrating a newly developed BAC-based physical mapping resource for Lolium ...
Lolium perenne (perennial ryegrass) is the most widely cultivated forage and amenity grass species in temperate areas worldwide and there is a need to understand the genetic... -
Repeat associated mechanisms of genome evolution and function revealed by the...
Understanding the mechanisms driving lineage-specific evolution in both primates and rodents has been hindered by the lack of sister clades with a similar phylogenetic structure... -
Exploiting the ZIP4 homologue within the wheat Ph1 locus has identified two l...
Despite possessing related ancestral genomes, hexaploid wheat behaves as a diploid during meiosis. The wheat Ph1 locus promotes accurate synapsis and crossover of homologous...
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