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MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is driven by metabolic changes in pancreatic cells caused by oncogenic mutations and dysregulation of p53. PDAC cell lines and... -
Unraveling the subtleties of β-(1→3)-glucan phosphorylase specificity in the ...
Glycoside phosphorylases (GPs) catalyze the phosphorolysis of glycans into the corresponding sugar 1-phosphates and shortened glycan chains. Given the diversity of natural... -
Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the b...
Acute myeloid leukemia (AML) is an age-related disease that is highly dependent on the bone marrow (BM) microenvironment. With increasing age, tissues accumulate senescent...
