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DNA assembly standards: Setting the low-level programming code for plant biot...
Synthetic Biology is defined as the application of engineering principles to biology. It aims to increase the speed, ease and predictability with which desirable changes and... -
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses
Biomarkers with high reproducibility and accurate prediction performance can contribute to comprehending the underlying pathogenesis of related complex diseases and further... -
Towards better models and mechanistic biomarkers for drug-induced gastrointes...
Adverse drug reactions affecting the gastrointestinal (GI) tract are a serious burden on patients, healthcare providers and the pharmaceutical industry. GI toxicity encompasses... -
MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is driven by metabolic changes in pancreatic cells caused by oncogenic mutations and dysregulation of p53. PDAC cell lines and... -
Network Biology Approaches to Identify Molecular and Systems-Level Difference...
The field of systems biology endeavors to map, study, and simulate cellular systems and their underlying mechanisms. The internal mechanisms of biological systems can be... -
SignaLink: Multilayered Regulatory Networks
Biological networks are graphs used to represent the inner workings of a biological system. Networks describe the relationships of the elements of biological systems using edges... -
The use of quantitative imaging to investigate regulators of membrane traffic...
Expansion of gene families facilitates robustness and evolvability of biological processes but impedes functional genetic dissection of signalling pathways. To address this,... -
Evaluation of gene expression of different molecular biomarkers of stress res...
The paper reports the results of a laboratory test on the bioaccumulation and toxicological effects of sub-lethal soil concentration of copper, a widely used fungicide in... -
Unraveling the subtleties of β-(1→3)-glucan phosphorylase specificity in the ...
Glycoside phosphorylases (GPs) catalyze the phosphorolysis of glycans into the corresponding sugar 1-phosphates and shortened glycan chains. Given the diversity of natural... -
Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the b...
Acute myeloid leukemia (AML) is an age-related disease that is highly dependent on the bone marrow (BM) microenvironment. With increasing age, tissues accumulate senescent... -
Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice R...
Salmonella enterica serovar Typhi causes typhoid fever only in humans. Murine infection with S. Typhimurium is used as a typhoid model, but its relevance to human typhoid is... -
SpikeletFCN: Counting Spikelets from Infield Wheat Crop Images Using Fully Co...
Currently, crop management through automatic monitoring is growing momentum, but presents various challenges. One key challenge is to quantify yield traits from images captured... -
Experimental evidence for rapid genomic adaptation to a new niche in an adapt...
A substantial part of biodiversity is thought to have arisen from adaptive radiations in which one lineage rapidly diversified into multiple lineages specialized to many... -
Integration of transcriptomic and metabolic data reveals hub transcription fa...
Drought is one of the most important environmental stresses that effects crop productivity in many agricultural regions. Sunflower is tolerant to drought conditions but the... -
Population Structure of Red Clover Ecotypes Collected from Europe and Asia
Red clover (Trifolium pratense L.) is a highly adaptable species, with a wide geographic distribution. At the genetic level, wild ecotypes possess high variability, which...
