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A four-group urine risk classifier for predicting outcomes in patients with p...
Objectives To develop a risk classifier using urine‐derived extracellular vesicle (EV)‐RNA capable of providing diagnostic information on disease status prior to biopsy, and... -
NODULE INCEPTION Recruits the Lateral Root Developmental Program for Symbioti...
To overcome nitrogen deficiencies in the soil, legumes enter symbioses with rhizobial bacteria that convert atmospheric nitrogen into ammonium. Rhizobia are accommodated as... -
A world of opportunities with nanopore sequencing
Oxford Nanopore Technologies' MinION sequencer was launched in pre-release form in 2014 and represents an exciting new sequencing paradigm. The device offers multi-kilobase... -
Harnessing plant metabolic diversity
Advances in DNA sequencing and synthesis technologies in the twenty-first century are now making it possible to build large-scale pipelines for engineering plant natural product... -
Opening options for material transfer
The Open Material Transfer Agreement is a material-transfer agreement that enables broader sharing and use of biological materials by biotechnology practitioners working within... -
Adaptation and conservation insights from the koala genome
The koala, the only extant species of the marsupial family Phascolarctidae, is classified as ‘vulnerable’ due to habitat loss and widespread disease. We sequenced the koala... -
Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations ov...
Crop disease outbreaks are often associated with clonal expansions of single pathogenic lineages. To determine whether similar boom-and-bust scenarios hold for wild... -
Albugo candida race diversity, ploidy and host-associated microbes revealed ...
Physiological races of the oomycete Albugo candida are biotrophic pathogens of diverse plant species, primarily the Brassicaceae, and cause infections that suppress host... -
Exploiting the ZIP4 homologue within the wheat Ph1 locus has identified two l...
Despite possessing related ancestral genomes, hexaploid wheat behaves as a diploid during meiosis. The wheat Ph1 locus promotes accurate synapsis and crossover of homologous... -
NLR diversity, helpers and integrated domains: making sense of the NLR IDentity
Plant innate immunity relies on genetically predetermined repertoires of immune receptors to detect pathogens and trigger an effective immune response. A large proportion of... -
A chromosome conformation capture ordered sequence of the barley genome
The International Barley Genome Sequencing Consortium reports sequencing and assembly of a reference genome for barley, Hordeum vulgare. -
Y Chromosome Sequences Reveal a Short Beringian Standstill, Rapid Expansion, ...
The Americas were the last inhabitable continents to be occupied by humans, with a growing multidisciplinary consensus for entry 15–25 thousand years ago (kya) from northeast... -
Heterarchy of transcription factors driving basal and luminal cell phenotypes...
Heterarchy of transcription factors driving basal and luminal cell phenotypes in human urothelium -
Zinc finger nuclease-mediated precision genome editing of an endogenous gene ...
Sequence‐specific nucleases have been used to engineer targeted genome modifications in various plants. While targeted gene knockouts resulting in loss of function have been... -
Genomics of habitat choice and adaptive evolution in a deep-sea fish
Intraspecific diversity promotes evolutionary change, and when partitioned among geographic regions or habitats can form the basis for speciation. Marine species live in an... -
New approaches for assembly of short-read metagenomic data
In recent years, the use of longer-range read data combined with advances in assembly algorithms has stimulated big improvements in the contiguity and quality of genome... -
Sixteen diverse laboratory mouse reference genomes define strain-specific hap...
We report full-length draft de novo genome assemblies for 16 widely used inbred mouse strains and find extensive strain-specific haplotype variation. We identify and... -
Biodiversity-function relationships in methanogenic communities
Methanogenic communities play a crucial role in carbon cycling and biotechnology (anaerobic digestion), but our understanding of how their diversity, or composition in general,... -
The ash dieback invasion of Europe was founded by two genetically divergent i...
Accelerating international trade and climate change make pathogen spread an increasing concern. Hymenoscyphus fraxineus, the causal agent of ash dieback, is a fungal pathogen... -
Defining Cell Identity with Single-Cell Omics
Cells are a fundamental unit of life, and the ability to study the phenotypes and behaviors of individual cells is crucial to understanding the workings of complex biological...
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