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The transcriptional landscape of polyploid wheat
The coordinated expression of highly related homoeologous genes in polyploid species underlies the phenotypes of many of the world’s major crops. Here we combine extensive gene... -
Transcriptional and environmental control of bacterial denitrification and N2...
In oxygen-limited environments, denitrifying bacteria can switch from oxygen-dependent respiration to nitrate (NO3−) respiration in which the NO3− is sequentially reduced via... -
BioCIDER: a Contextualisation InDEx for biological Resources discovery
The vast, uncoordinated proliferation of bioinformatics resources (databases, software tools, training materials etc.) makes it difficult for users to find them. To facilitate... -
Single cell ecology
Cells are the building blocks of life, from single-celled microbes through to multi-cellular organisms. To understand a multitude of biological processes we need to understand... -
Genomic prediction unifies animal and plant breeding programs to form platfor...
The rate of annual yield increases for major staple crops must more than double relative to current levels in order to feed a predicted global population of 9 billion by 2050.... -
Community-Driven Data Analysis Training for Biology
The primary problem with the explosion of biomedical datasets is not the data itself, not computational resources, and not the required storage space, but the general lack of... -
Speed breeding in growth chambers and glasshouses for crop breeding and model...
To meet the challenge of feeding a growing population, breeders and scientists are continuously looking for ways to increase genetic gain in crop breeding. One way this can be... -
Developmentally regulated autophagy is required for eye formation in Drosophila
The compound eye of the fruit fly Drosophila melanogaster is one of the most intensively studied and best understood model organs in the field of developmental genetics. Herein... -
SPECTRE: a Suite of PhylogEnetiC Tools for Reticulate Evolution
Split-networks are a generalization of phylogenetic trees that have proven to be a powerful tool in phylogenetics. Various ways have been developed for computing such networks,... -
Shifting the limits in wheat research and breeding using a fully annotated re...
An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding... -
Data management and best practice for plant science
Plant research produces data in a profusion of types and scales, and in ever-increasing volume. What are the challenges and opportunities presented by data management in... -
Speed breeding is a powerful tool to accelerate crop research and breeding
The growing human population and a changing environment have raised significant concern for global food security, with the current improvement rate of several important crops... -
A comprehensive genomic history of extinct and living elephants
Elephantids are the world’s most iconic megafaunal family, yet there is no comprehensive genomic assessment of their relationships. We report a total of 14 genomes, including 2... -
Practical Computational Reproducibility in the Life Sciences
AUTHOR CONTRIBUTIONS -
Chromosome assembly of large and complex genomes using multiple references
Despite the rapid development of sequencing technologies, the assembly of mammalian-scale genomes into complete chromosomes remains one of the most challenging problems in... -
Identification of genetic variants affecting vitamin D receptor binding and a...
Large numbers of statistically significant associations between sentinel SNPs and case-control status have been replicated by genome-wide association studies. Nevertheless, few...
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